Grisovin FP 250mg

About Grisovin FP 250mg

Highly effective regardless of the affected area with internal use type! It is an inexpensive and easy-to-follow antifungal drug.

• It is an oral mycosis drug that can be used for more effective treatment.
• The active ingredient suppresses the division and growth of dermatophytes to prevent erosion.
• The price is lower than follow-on drugs, making it easier to continue for a long period of time.

Grisovin FP  250mg is a dermatomycotic drug manufactured by GlaxoSmithKline Pharma, a major British pharmaceutical company. The active ingredient, griseofulvin, is an antifungal antibiotic that was discovered in 1939 and has a very long history as a treatment for mycoses.

Griseofulvin was discontinued in USA in 2008, but it is still widely prescribed overseas and can be used with confidence.

Features of Grisovin FP 250mg

The main feature of Grisovin FP is that it is an oral antimycotic drug. Another advantage of Grisovin FP is that it differs from topical drugs that are applied directly to the affected area.

For topical medicines, the active ingredients must be thoroughly blended into the skin and penetrated, but it has been considered difficult to treat areas where it is difficult to apply directly to the affected area, such as the inside of the nail or pubic area.

Since Grisovin FP is an oral drug, the active ingredient can be distributed throughout the body through the bloodstream, enabling treatment from the inside of the body. In fact, griseofulvin, which is the active ingredient of Grisovin FP, has low keratin affinity and is not highly absorbed through the skin. In this respect, it can be said that griseofulvin is more effective when taken orally.

One point to note is that griseofulvin has the property of being difficult to dissolve in water. You can speed up the dissolution rate and make it easier to absorb by taking it with food containing a lot of fat or milk. However, it is recommended to take this medicine with water or lukewarm water, so please consult your doctor about how to take this medicine.

Prevents cell division of dermatophytes and suppresses growth

The two effects of griseofulvin, the active ingredient of Grisovin FP 250mg, suppress the division and growth of dermatophytes that cause tinea pedis.

The first is the binding action with the microtubules of dermatophytes. Microtubules are essential cytoskeleton for dermatophyte cell division, and griseofulvin binds to these microtubules to prevent dermatophytes from proceeding with division.

The second is the binding action with protein, which is a source of nutrition for dermatophytes. When keratin, a protein necessary for the growth of dermatophytes, binds to griseofulvin, the dermatophytes become nutrient deficient and their growth is stopped.

Thus, griseofulvin does not kill dermatophytes, but rather suppresses their activity and growth.

Therefore, it is necessary to take it continuously for a long time until the skin and nails are reborn without being eroded by dermatophytes. Don’t self-diagnose whether you’re cured or not, be sure to see a doctor.

It is a therapeutic drug that is cheaper than subsequent antifungal drugs and has a track record of use.

Griseofulvin was discontinued in USA in 2008. Please be assured that this is due to the discontinuation of the import of griseofulvin raw materials and is not a safety issue. It is still widely used overseas as a treatment for fungal diseases.

Effects of Grisovin FP 250mg

Effect/Efficacy

Improvement of skin symptoms caused by dermatophytes such as ringworm and athlete’s foot.

Grisovin FP 250mg is a mycosis drug that treats ringworm, tinea, and itching caused by dermatophytes, such as ringworm and athlete’s foot. By continuing to take this medicine at a fixed time every day, it suppresses the growth of dermatophytes and improves symptoms. However, it takes a certain amount of time to cure completely, and it is said that several months are required for skin symptoms, and half a year to a year is required for nail symptoms.

Griseofulvin was found to be absorbed more efficiently when taken with fat. When taking this medicine, you can take the active ingredient into your body more efficiently by taking it together with fats such as butter and high-fat foods such as dairy products.

How to take Grisovin FP 250mg

1 Dose

1 or 2 tablets (250-500mg as “griseofulvin”)

Number of doses per day

1-2 times

Duration of use

A few months for skin symptoms and 1 to 2 years for nails

About when to take

Grisovin FP 250mg is a drug that is not particularly affected by food. Therefore, it can be taken before or after meals, but it is recommended to take it at a fixed time every day.

Concomitant use with alcohol may over-enhance the action of griseofulvin, the active ingredient. Avoid drinking alcohol while taking Grisovin FP.

About the active ingredient of Grisovin FP 250mg

Griseofulvin prevents fungal division and growth

Griseofulvin is a component that acts bacteriostatically against terbinafine, which acts bactericidal. When dermatophytes that cause ringworm and athlete’s foot divide, this medicine prevents dermatophytes from dividing and multiplying by binding to the microtubules at the center of the division apparatus.

Since it does not have the effect of killing the bacteria itself, long-term continuous use is essential, but it is a highly safe therapeutic drug that is also approved for use in children.

Grisovin FP 250mg Side Effects

Major side effects

Headache, dizziness, rash, drowsiness, etc.

Grisovin FP may cause symptoms such as dizziness and drowsiness. Therefore, while taking Grisovin FP, avoid driving a car or performing dangerous work as much as possible.

Also, if hypersensitivity symptoms such as angioedema or photosensitivity occur, stop taking Grisovin FP.

Rare side effects

SLE-like symptoms, toxic epidermal necrolysis, peripheral neuritis, porphyria, confusion, jaundice, liver dysfunction, etc.

If you experience serious side effects such as pain in muscles and joints (SLE-like symptoms), hot skin (toxic epidermal necrolysis), and numbness in limbs (peripheral neuritis), take Grisovin FP. Please consult a doctor as soon as you stop taking this medicine.

Precautions for Grisovin FP 250mg

• Careful administration
  • People taking coumarin-based anticoagulants (warfarin, etc.)
  • People taking barbituric acid derivatives (such as phenobar)
  • People taking contraceptives (Marvelon, Tricular, Yaz, etc.)
• Persons who should not take
  • Persons with a history of hypersensitivity to griseofulvin
  • People with liver dysfunction
  • people with porphyria
  • Pregnant or potentially pregnant
• Contraindicated drugs
  • There are no reports of contraindications for concomitant use, but there are some drugs that require caution when used concomitantly.
  • Coumarin-based anticoagulants (warfarin, etc.)
  • Barbituric acid derivatives (such as phenobar)
  • Contraceptives (Marvelon, Tricular, Yaz, etc.)

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Shipping/packaging

Country of origin
India

Estimated time of arrival
7-14 days

• Delivery may be delayed due to weather in the country of origin or holidays of vendors in the country of origin.
• Delivery may be delayed in some areas such as remote islands and remote islands.